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chromatin  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc chromatin
    Chromatin, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 682 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/e2f/E2F-1+Antibody/pm42830288-362-7-13
    Average 96 stars, based on 682 article reviews
    chromatin - by Bioz Stars, 2026-11
    96/100 stars

    Images

    Related Articles

    Control:

    Article Title: Anti-tumor Effects of Erlotinib via Thymidylate Synthase Down-regulation in Pancreatic Cancer Cells.
    Article Snippet: Background/Aim: In pancreatic cancer, gemcitabine and EGFR tyrosine kinase inhibitors (EGFR-TKIs) are common chemotherapy options.. Reports have shown that EGFR-TKIs suppress the expression of thymidine synthase (TS), an important enzyme for DNA biosynthesis, and increase sensitivity to gemcitabine in lung cancer.. However, no such reports have been made in pancreatic cancer.

    Bioprocessing:

    Article Title: Repurposing Suan-Zao-Ren-Tang as anticancer agents in apoptotic sensitization against non-small cell lung cancer cell lines through amplification of spindle assembly checkpoint activation
    Article Snippet: The chemicals and β-tubulin monoclonal antibody were from Sigma-Aldrich (St. Louis, MO). .. The following monoclonal antibodies were used: Bax, Caspase 7, Caspase 8, Caspase 9, E2F, Cdk1 Tyr15 , Cdk1 Thr161 (Cell Signaling Technology, Beverly, MA), BUB1, BUB3, BUBR1, Cyclin D1 (ABCam, Cambridge, MA), caspase-3 (Imgenex, San Diego, CA) and MPM2 (Millipore, Burlington, MA). .. The other antibodies were from Santa Cruz Biotechnology, Santa Cruz, CA. Bio-Rad protein assay kit was purchased from Bio-Rad (Hercules, CA).

    Cell-Signaling:

    Article Title: Repurposing Suan-Zao-Ren-Tang as anticancer agents in apoptotic sensitization against non-small cell lung cancer cell lines through amplification of spindle assembly checkpoint activation
    Article Snippet: The chemicals and β-tubulin monoclonal antibody were from Sigma-Aldrich (St. Louis, MO). .. The following monoclonal antibodies were used: Bax, Caspase 7, Caspase 8, Caspase 9, E2F, Cdk1 Tyr15 , Cdk1 Thr161 (Cell Signaling Technology, Beverly, MA), BUB1, BUB3, BUBR1, Cyclin D1 (ABCam, Cambridge, MA), caspase-3 (Imgenex, San Diego, CA) and MPM2 (Millipore, Burlington, MA). .. The other antibodies were from Santa Cruz Biotechnology, Santa Cruz, CA. Bio-Rad protein assay kit was purchased from Bio-Rad (Hercules, CA).

    Western Blot:

    Article Title: Yes-activated protein promotes primary resistance of BRAF V600E mutant metastatic colorectal cancer cells to mitogen-activated protein kinase pathway inhibitors
    Article Snippet: .. Western blots were probed with specific antibodies against CDK6, ERK, P-ERK (Cell Signaling Technology, CST), SGK1 (Hua An Organism), Bcl-2 (Abcam), Cyclin D1, YAP (Santa), β-actin (CST), LaminB1 (CST), PARP (CST), α-Tubulin (CST), pRb (S807/811) (CST), E2F (CST), and Mcl-1 (CST). .. Blotting results were visualized using a chemiluminescent detection system (Pierce ECL Substrate Western Blot Detection System, Thermo Scientific, IL, USA) and exposure to autoradiography film (Kodak XAR).



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    Image Search Results


    (A, B) Kaplan–Meier plot showing that overexpression of E2F1 is associated with shorter overall survival (A) and progression-free interval (B) in endometrial cancer cohort. (C, D) Kaplan–Meier plot showing that co-overexpression of LARP1 and E2F1 is associated with shorter overall survival (C) and progression-free interval (D) in endometrial cancer cohort. (E) Spearman correlation analysis shows a correlation between LARP1 and E2F1 in endometrial cancer patients.

    Journal: bioRxiv

    Article Title: “Targeting LARP1 Enhances Carboplatin Sensitivity and Suppresses Tumor Growth in Endometrial Cancer”

    doi: 10.64898/2026.03.22.713473

    Figure Lengend Snippet: (A, B) Kaplan–Meier plot showing that overexpression of E2F1 is associated with shorter overall survival (A) and progression-free interval (B) in endometrial cancer cohort. (C, D) Kaplan–Meier plot showing that co-overexpression of LARP1 and E2F1 is associated with shorter overall survival (C) and progression-free interval (D) in endometrial cancer cohort. (E) Spearman correlation analysis shows a correlation between LARP1 and E2F1 in endometrial cancer patients.

    Article Snippet: Cells were then incubated overnight at 4 °C with the following primary antibodies: LARP1 (Cat. No. sc-515873; 1:200 dilution; Santa Cruz Biotechnology, Dallas, TX, USA) and E2F1 (Cat. No. 3742S; 1:400 dilution; Cell Signaling Technology, Danvers, MA, USA).

    Techniques: Over Expression

    (A, B) Immunoblot analysis showing the protein expression of LARP1 and E2F1 after transfecting ISHI (A) and HEC-1A (B) cells with control or LARP1 siRNA. β-actin was used as a loading control. (C) Images representing immunofluorescence staining of LARP1 (green) and E2F1 (red) in HEC-1A cells after transfection with control or LARP1 siRNA. DAPI was used as a counter stain. Scale bar = 50 µm.

    Journal: bioRxiv

    Article Title: “Targeting LARP1 Enhances Carboplatin Sensitivity and Suppresses Tumor Growth in Endometrial Cancer”

    doi: 10.64898/2026.03.22.713473

    Figure Lengend Snippet: (A, B) Immunoblot analysis showing the protein expression of LARP1 and E2F1 after transfecting ISHI (A) and HEC-1A (B) cells with control or LARP1 siRNA. β-actin was used as a loading control. (C) Images representing immunofluorescence staining of LARP1 (green) and E2F1 (red) in HEC-1A cells after transfection with control or LARP1 siRNA. DAPI was used as a counter stain. Scale bar = 50 µm.

    Article Snippet: Cells were then incubated overnight at 4 °C with the following primary antibodies: LARP1 (Cat. No. sc-515873; 1:200 dilution; Santa Cruz Biotechnology, Dallas, TX, USA) and E2F1 (Cat. No. 3742S; 1:400 dilution; Cell Signaling Technology, Danvers, MA, USA).

    Techniques: Western Blot, Expressing, Control, Immunofluorescence, Staining, Transfection

    (A) Phylogenetic analysis of the E2F/DP gene family in tomato, rice, soybean, maize, and Arabidopsis thaliana . The E2F/DP genes were classified into three major groups: E2F-type, DEL-type, and DP-type. (B) Chromosomal localization of OsE2F/DP genes. Chromosome numbers are shown at the top, and the scale on the left indicates physical distance in megabases (Mb). A genetic interval of approximately 350 kb was set to accurately illustrate the distribution of the genes.

    Journal: Frontiers in Plant Science

    Article Title: Identification of E2F/DP gene family and their expression analysis under cold stress in rice

    doi: 10.3389/fpls.2026.1750382

    Figure Lengend Snippet: (A) Phylogenetic analysis of the E2F/DP gene family in tomato, rice, soybean, maize, and Arabidopsis thaliana . The E2F/DP genes were classified into three major groups: E2F-type, DEL-type, and DP-type. (B) Chromosomal localization of OsE2F/DP genes. Chromosome numbers are shown at the top, and the scale on the left indicates physical distance in megabases (Mb). A genetic interval of approximately 350 kb was set to accurately illustrate the distribution of the genes.

    Article Snippet: In Medicago, salt stress has been shown to promote the co-expression of E2F and DP genes ( ).

    Techniques:

    Conserved domains, motif patterns, and gene structures of rice E2F/DP genes. (A) The motif patterns of OsE2F/DP members are shown. (B) Conserved domains are indicated by colored boxes, with four conserved domains represented by distinct colors. The scale bar at the bottom of the panel allows estimation of the relative lengths of gene structures and motif components. (C) The gene structures of OsE2F/DP genes are illustrated, where green boxes represent the untranslated regions (UTRs) at the 5′ and 3′ ends, yellow boxes denote the coding sequences (CDSs), and black lines indicate introns.

    Journal: Frontiers in Plant Science

    Article Title: Identification of E2F/DP gene family and their expression analysis under cold stress in rice

    doi: 10.3389/fpls.2026.1750382

    Figure Lengend Snippet: Conserved domains, motif patterns, and gene structures of rice E2F/DP genes. (A) The motif patterns of OsE2F/DP members are shown. (B) Conserved domains are indicated by colored boxes, with four conserved domains represented by distinct colors. The scale bar at the bottom of the panel allows estimation of the relative lengths of gene structures and motif components. (C) The gene structures of OsE2F/DP genes are illustrated, where green boxes represent the untranslated regions (UTRs) at the 5′ and 3′ ends, yellow boxes denote the coding sequences (CDSs), and black lines indicate introns.

    Article Snippet: In Medicago, salt stress has been shown to promote the co-expression of E2F and DP genes ( ).

    Techniques:

    (A) Collinearity analysis of homologous OsE2F/DP genes in rice. In the figure, syntenic blocks across the entire rice genome are shown with a gray background, while red curves connect the pairs of homologous OsE2F/DP genes. (B) Synteny relationships of E2F/DP genes among Arabidopsis thaliana , rice, and sorghum. Gray lines in the background represent collinear gene pairs between the two species, whereas the E2F/DP collinear gene pairs are highlighted with reddish-brown lines.

    Journal: Frontiers in Plant Science

    Article Title: Identification of E2F/DP gene family and their expression analysis under cold stress in rice

    doi: 10.3389/fpls.2026.1750382

    Figure Lengend Snippet: (A) Collinearity analysis of homologous OsE2F/DP genes in rice. In the figure, syntenic blocks across the entire rice genome are shown with a gray background, while red curves connect the pairs of homologous OsE2F/DP genes. (B) Synteny relationships of E2F/DP genes among Arabidopsis thaliana , rice, and sorghum. Gray lines in the background represent collinear gene pairs between the two species, whereas the E2F/DP collinear gene pairs are highlighted with reddish-brown lines.

    Article Snippet: In Medicago, salt stress has been shown to promote the co-expression of E2F and DP genes ( ).

    Techniques: